Electrochemical detection of endotoxin using recombinant factor C zymogen
نویسندگان
چکیده
منابع مشابه
Novel electrochemical sensor for endotoxin detection
Endotoxin, a component of many bacteria, is highly toxic when injected into humans or animals. Since endotoxin is widespread in the environment, any drug, fluid or device intended to be injected or in close contact with live tissues must be tested to assure that it is LPS-free. Currently, the method most extensively used for endotoxin detection (LAL; Limulus Amebocyte Lysate) is sensitive but l...
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As a potent inflammatory agent, endotoxin is a key analyte of interest for studies of lung ailments in domestic environments and occupational settings with organic dust. A relatively unexplored advance in endotoxin exposure assessment is the use of recombinant factor C (rFC) from the Limulus pathway in a fluorometric assay. In this study, we compared airborne endotoxin concentrations in laborat...
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ژورنال
عنوان ژورنال: Electrochemistry Communications
سال: 2010
ISSN: 1388-2481
DOI: 10.1016/j.elecom.2010.05.028